Compound Inhibitors of HIV-1 NL4-3 Vpu. Viruses. 15 April 2022. PMID: 35458546
Robinson C.A., Lyddon T.D., GilH.M., Evans D.T., Kuzmichev Y.V., Richard J., Finzi A., Welbourn S., Rasmussen L., Nebane N.M., Gupta V.V., Ananthan S., Cai Z., Wonderlich E.R., Augelli-Szafran C.E., Bostwick R., Ptak R.G., Schader S.M., Johnson M.C.
Novel role of UHRF1 in the epigenetic repression of the latent HIV-1. EBioMedicine. 2022 May;79:103985. doi: 10.1016/j.ebiom.2022.103985. Epub 2022 Apr 14. PMID: 35429693
Verdikt R, Bendoumou M, Bouchat S, Nestola L, Pasternak AO, Darcis G, Avettand-Fenoel V, Vanhulle C, Aït-Ammar A, Santangelo M, Plant E, Douce VL, Delacourt N, Cicilionytė A, Necsoi C, Corazza F, Passaes CPB, Schwartz C, Bizet M, Fuks F, Sáez-Cirión A, Rouzioux C, De Wit S, Berkhout B, Gautier V, Rohr O, Van Lint C.
Detection of the HIV-1 accessory proteins Nef and Vpu by flow cytometry represents a new tool to study their functional interplay within a single infected CD4+ T cell. J Virol. 2022, Mar 23;96(6):e0192921. doi: 10.1128/jvi.01929-21. Epub 2022 Jan 26. PMID: 35080425
Prévost J., Richard J., Gasser R., Medjahed H., Kirchhoff F., Hahn B.H., Kappes J.C., Ochsenbauer C., Duerr R. and Finzi A.
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Jurkat-Derived (J-Lat, J1.1, and Jurkat E4) and CEM-Derived T Cell Lines (8E5 and ACH-2) as Models of Reversible Proviral Latency. HIV Reservoirs. Methods Mol Biol. 2022;2407:3-15.doi: 10.1007/978-1-0716-1871-4_1. PMID: 34985653.
Rodari A., Poli G., Van Lint C.
HIV-1 envelope glycoproteins proteolytic cleavage protects infected cells from ADCC mediated by plasma from infected individuals. Viruses, 2021 Nov 6, 13(11), 2236 https://doi.org/10.3390/v13112236.
Prévost J., Medjahed H., Vézina D., Chen HC., Hahn BH., Smith III AB and Finzi A.
Interleukin-10 contributes to reservoir establishment and persistence in antiretroviral therapy-treated, SIV-infected macaques. J Clin Invest. 2022. Apr 15;132(8):e155251. doi: 10.1172/JCI155251.PMID: 35230978
Harper J., RibeiroS.P., Chan C.N., Aid A., Deleage C., Micci L., Pino M., Cervasi B., Raghunathan G., Rimmer E., Ayanoglu G., Wu G., Shenvi N., Barnard R.J., Del Prete G., Busman-Sahay K., Silvestri G., Kulpa D., Bosinger S., Easley K., Howell B.J., Gorman D., Hazuda D.J., Estes J.D., Sekaly R.P., Paiardini M.
Characterization of Human Immunodeficiency Virus (HIV-1) Envelope Glycoprotein Variants Selected for Resistance to a CD4-Mimetic Compound. J Virol. 2022 Sep 14;96(17):e0063622. doi: 10.1128/jvi.00636-22. Epub 2022 Aug 18. PMID: 35980207.
Anang S., Richard J, Bourassa C.B., Goyette G, Chiu T-J, Chen H-C, Smith A.B. III, Madani N., Finzi A., Sodroski J.
Reprogramming dysfunctional CD8+ T cells to promote properties associated with natural HIV control. J Clin Invest. 2022, Jun 1;132(11):e157549. doi: 10.1172/JCI157549. PMID: 35380989.
Perdomo-Celis F., Passaes C., Monceaux V., Volant S., de Truchis F.B.P., Morgane Marcou, Bourdic K., Weiss L., Jung C., Bourgeois C., Goujard C., Meyer L., Muller-Trutwin M., Lambotte O., Saez-Cirion A.
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Ex Vivo Differentiation of Resting CD4+ T Lymphocytes Enhances Detection of Replication Competent HIV-1 in Viral Outgrowth Assays. HIV Reservoirs. Methods Mol Biol. 2022;2407:315-331. doi: 10.1007/978-1-0716-1871-4_21. PMID: 34985673.
Wonderlich E., Reece M., Kulpa D.
Limited impact of fingolimod treatment during the initial weeks of ART in SIV-infected rhesus macaques.
Pino M, Pagliuzza A, Pampena MB, Deleage C, Viox E, Nguyen K, Shim I, Zhang A, Harper JL, Samer S, King CT, Cervasi B, Gill KP, Ehnert S, Jean SM, Freeman, ML, Lifson JD, Kulpa D, Betts MR, Chomont N, Lederman MM, Paiardini M.
BOOK
Near-Full-Length Single-Genome HIV-1 DNA Sequencing. HIV Reservoirs. Methods Mol Biol. 2022;2407:357-364.doi: 10.1007/978-1-0716-1871-4_23. PMID: 34985675.
Lee G.Q., Lichterfeld M.
Hide and seek for HIV-infected CD4+ T cells, playing well comes with maturity. J Clin Invest. 2022. Apr1;132(7):1-4. Doi:101172/ICI157549. PMID:35362485.
Leyre L., Jones R.B.
The role of Cd101-expressing CD4 T cells in HIV/SIV pathogenesis and persistence. PLoS Pathog. 2022, Jul 22;18(7):e1010723. doi10.1371/journal.ppat.1010723. eCollection 2022 Jul. PMID: 3586772 PMCID: PMC9348691DOI: 10.1371/journal.ppat.1010723
Strongin Z, Hoang TN, Tharp GK, Rahmberg AR, Harper JL, Nguyen K, Franchitti L, Cervasi B, Lee M, Zhang Z, Boritz EA, Silvestri G, Marconi VC, Bosinger SE, Brenchley JM, Kulpa DA, Paiardini M.
Single center, open label dose escalating trial evaluating once weekly oral ixazomib in ART-suppressed, HIV positive adults and effects on HIV reservoir size in vivo. EClinicalMedicine. 2021 Nov 29;42:101225. doi: 10.1016/j.eclinm.2021.101225. eCollection 2021. PMID: 34901797
Cummins NW, Baker J, Chakraborty R, Dean PG, Garcia-Rivera E, Krogman A, Kumar S, Kuzmichev YV, Laird GM, Landay A, Lichterfeld M, Mahmood M, Martinson J, Maynes M, Natesampillai S, Rajkumar V, Rassadkina Y, Kristen Ritter KD, Rivera CG, Rizza SA, Subramanian K, Tande AJ, Wonderlich ER, Whitaker JA, Zeuli J, Badley AD .“
Parallel analysis of transcription, integration, and sequence of single HIV-1 proviruses. Cell, 2022, Jan 20; doi: 10.1016/j.cell.2021.12.011. Epub 2022 Jan 12. PMID:35026153.
Einkauf K.B., Osborn M.R., Gao C., Sun W., Sun X., Lian X., Parsons E.M., Galdkov,G.T,, Seiger KW,Blackmer J.E., Jliang C. Yuki S.A,. Rosenberg E.S., Yu X.G., Lichterfeld M.
Temsavir treatment of HIV-1-infected cells decreases envelope glycoprotein recognition by broadly neutralizing antibodies. mBio 2022 Jun28;13(3):e0057722.dol:10.128/mBio.00577-22. PMID: 3547564 PMCID: PMC9239219DOI: 10.1128/mbio.00577-22
Boutin M, Venzina D, Ding S, Prevost J, Laumaea A, Marchitto L, Anand SP, Medjahed H, Gendron-Lapage G, Bourassa C, Goyette G, Clark A, Richard J, Finzi A.
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TGF-β Signaling Supports HIV Latency in a Memory CD4+ T Cell Based In Vitro Model. HIV Reservoirs Methods Mol Biol. 2022;2407:69-79. doi: 10.1007/978-1-0716-1871-4_6. PMID: 34985658.
Bergstresser Sydney, Deanna Kulpa.